Tuesday, September 20, 2011

Progeria

Progeria
The word “Progeria” comes from the Greek Progeros meaning “prematurely old.” Progeria is an extremely rare, fatal genetic condition. This disease happens only to children usually beginning in their first two years of life, it accelerates the process of aging to about eight times the normal rate.  The average life expectancy of a child with Progeria is about 13 years old, but some can die at a younger age or live up to 20 or even 40 years longer. As of right now there is no cure for Progeria, children with this disease are at high risk of a heart attack or stroke. Even though it is believed that Progeria is a genetic disease it is not considered to be inherited, some people believe it is caused by mutation during conception. According to other recourses, only about 1 in 8 million children have Progeria. Only 54 cases of Progeria have been reported worldwide, but believed that there are up to 150 more cases undocumented.

Some signs and symptoms of the disease Progeria are; 
·         slowed growth,
·         below average height and weight,
·         a narrowed face and beaked nose,
·         thin lips,
·         visible veins,
·          high pitched voice,
·          delayed and abnormal tooth formation,
·          large head size,
·          stiff joints,
·          hip dislocation,
·          arthritis,
·          irregular heart beat.
            Newborns with Progeria usually are born as normal babies, but they start to develop distinctive features very fast. There are two major types of Progeria. The first one is known as rare Hutchinson-Gilford syndrome and it is a very rare occurrence. It sets in early childhood. The second type is called Werner's syndrome. This condition sets in later in life. There is a third variety too, where Progeria occurs with Hallerman-Streiff-François syndrome. In this type, dwarfism is a prominent feature. It is believed that Progeria can be the result of Lamin, a gene mutation, when its component cytosine is replaced by thyamine, this is the closest thing that could be one of the causes. Progeria is the rarest genetic disease to ever be discovered.

4 comments:

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